Tedd-
I've got 285's (tires) on the burb with 4.11 gears. I think it originally had 235's, but the PO switched them out before I bought it.
The truck "shows" that it gets 12.X mpg on my mixed speed (county highways with some slow-downs for small towns.) commute to work, but it may in fact be better and because of the tires I'm not "seeing it on paper". We got 9.8mpg on the trip to and from Travis'. We had 4 guys and all their gear in the truck plus three snow/grader blades in the back and 4 tractors on a tandem axle car hauler both ways.
As is typical with 4.10 gears, the truck drove great and towed that load like it was nothin'. I also tow an 8,000 boat with it in the summer and it does fine with that, (It's rated to tow #10,000) but next time I'll buy the 3.73 gears and take the hit in the towing dept. as 99% of my 20,000 yearly miles are non-towing miles.
As Kraig says....
<FONT SIZE="-2">IMO, FWIW, YMMV, My $0.02, Yada, Yada, Yada...</FONT>