Rodney, here is the post I made back in in Oct 2012:
Here's why the full synthetic oil is ALWAYS better. Imagine all the little carbon chains we call oil floating around in a Qt of oil. When that oil comes from dinosaur oil, there are lots of different chains of all different sizes. For the sake argument, let's say they are golf balls, baseballs, and soccerballs. All the little golf balls do nothing but fill space. Yes the lubricate, but they are small enough to slip past rings, valve guides, seals and just quickly get burned up or get stuck somewhere they shouldn't be. All those soccerballs are even worse. They are to large to even really properly lubricate and mostly get broken up or never make to the tiny spaces we call clearances. It's all those baseballs that do all the work we want, lubricating while stay where we need them.
Full synthetic oil is engineered to be ALL baseballs (all the exact same carbon chain and all the same perfect size). Its still oil, it's just engineered and formed in a lab instead of under a pile of rocks we call earth. So you are already noticing the benefit of full syn oil. Because you are no longer burning off all those golf balls and breaking down those soccerballs (becoming sludge) which is why Dino oil is so high in detergents, to keep those broken down chains from sticking to your engine parts, which ironically means its passing more dirt and less oil through the oil passages the longer it's run. Why do you think they make full syn's that can run 15k miles? It's not breaking down or burning up!
So to answer the question, not only is it safe to switch, your SHOULD switch. And like said below, use Dino oil for break in or go full bore and use "break in oil".